Microsoft has really ramped up their support for Node.js over the past couple of years.
With the introduction of Node.js Tools For Visual Studio they've turned their super fancy IDE into a real contender in the Node development space.
Sure it has some rough edges (it is still in Beta after all), but it already makes the task of debugging node apps much nicer.
I presented a talk at the Gwinnett, Georgia, Microsoft User Group (GGMUG) meeting for May, 2014 about using Microsoft tools for Node development.
Here's a PDF of my slides.